Leukotriene D4

CAS No. 73836-78-9

Leukotriene D4( —— )

Catalog No. M35009 CAS No. 73836-78-9

Leukotriene D4 (LTD4) is a potent pro-inflammatory mediator formed from arachidonic acid, a bronchoconstrictor, and induces osteoclast senescence.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Leukotriene D4
  • Note
    Research use only, not for human use.
  • Brief Description
    Leukotriene D4 (LTD4) is a potent pro-inflammatory mediator formed from arachidonic acid, a bronchoconstrictor, and induces osteoclast senescence.
  • Description
    Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability.
  • In Vitro
    ——
  • In Vivo
    Leukotriene D4 (1.5, 3, 6, 12, 24 μg/paw; injected intradermally) causes edema and increases capillary permeability in a dose-related manner in mouse.Animal Model:21-24 g, Balb/c male mice Dosage:1.5, 3, 6, 12, 24 μg/paw Administration:Injected intradermally (10 μL was injected into the left hind paw)Result:Caused significant edematous response and dye extravasation at doses of 1.5-6 ~g/paw.
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite | Drug Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    73836-78-9
  • Formula Weight
    496.66
  • Molecular Formula
    C25H40N2O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [C@H](SC[C@@H](C(NCC(O)=O)=O)N)([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Smith LJ, et al. The effect of inhaled leukotriene D4 in humans. Am Rev Respir Dis. 1985 Mar;131(3):368-72.?
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